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Hyperalgesia and Allodynia: Situations of hyperalgesia and allodynia are already reported with opioid therapy of any period [see Warnings and Safeguards (5.eight)] QT prolongation/torsade de pointes: Conditions of QT prolongation and/or torsade de pointes have already been reported with tramadol use.Benzodiazepines: Benzodiazepines are like Z medic